effects of glp-1 receptor agonists on neurological complications of diabetes GLP-1 Receptor Agonists as Treatments for Type 2 Diabetes The Potential Indirect Impact of

Nevertheless, the cells had issues within the systems that normally remove reactive oxygen species from cells, reduced levels of mitochondrial superoxide dismutase (a protective enzyme against oxidative stress), and other factors that contribute to ongoing oxidative damage

Inactivation of GPX4 leads to accumulation of lipid ROS and induces ferroptosis 18,31

Selective degeneration of synapses in the dorsal cochlear nucleus of chinchilla following acoustic trauma and effects of antioxidant treatment

Experts also recommend that excessive alcohol and toxins be avoided

It enhances oxidative phosphorylation (OXPHOS) efficiency by stabilizing Complex I and ATP synthase activity, stimulates PGC-1-NRF1-TFAM-mediated biogenesis to replenish functional mitochondria, preserves mitochondrial membrane potential (m), inhibits mPTP opening, and modulates mitophagy through Parkin recruitment and LC3-II lipidation, thereby supporting both quantitative expansion and qualitative renewal of the mitochondrial network (Lu et al., 2025)

Consult with pharmacist, if available